国产综合一区二区三区,99香蕉国产精品偷在线观看,性色少妇AV蜜臀人妻无码,成版人app网站

您好,歡迎進入上海力敏實業(yè)有限公司網(wǎng)站!
一鍵分享網(wǎng)站到:
您現(xiàn)在的位置:首頁 >> 產(chǎn)品中心 >> 生化試劑、抗體、血清 >> 細胞因子 >> RD 3339-FB-025R&D供應商Recombinant Rat FGF basic 重組大鼠堿性成纖維細胞生長因子

R&D供應商Recombinant Rat FGF basic 重組大鼠堿性成纖維細胞生長因子

  • 更新時間:  2023-07-25
  • 產(chǎn)品型號:  RD 3339-FB-025
  • 簡單描述
  • Recombinant Rat FGF basic ,Recombinant Human FGF basic ,Recombinant Human KGF/FGF-7,Recombinant Human/Mouse FGF-8b
詳細介紹

DESCRIPTION
Source E. coliderived
Ala11Ser154
Accession # P13109
Nterminal
Sequence
Analysis
Ala11
Predicted Molecular
Mass
16.2 kDa
SPECIFICATIONS
Activity Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al. (1988) Cancer Res. 48:4266? Thomas, K. et
al. (1987) Methods Enzymol. 147:120.
The ED50 for this effect is typically 0.31.8
ng/mL.
Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method.
Purity >95%, by SDSPAGE
under reducing conditions and visualized by silver stain.
Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein. See Certificate of Analysis for
details.
PREPARATION AND STORAGE
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediay at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freezethaw
cycles.
l 12 months from date of receipt, 20
to 70
°C as supplied.
l 1 month, 2 to 8 °C under sterile conditions after reconstitution.
l 3 months, 20
to 70
°C under sterile conditions after reconstitution.
BACKGROUND
FGF basic (FGF2,
HBGF2)
is one of at least 22 mitogenic proteins of the FGF family, which show 35 60%
amino acid conservation (1 3).
Unlike other FGFs,
FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. Storage pools within the cell or on cell surface heparan sulfate proteoglycans
(HSPG) are likely. The predicted 18 kDa FGF basic isoform can be located in both the cytoplasm and the nucleus and is presumed to be the form secreted (4).
Transcription from alternate start sites produces 21 23
kDa forms found only in the nucleus. High and low molecular weight human FGF basic targets the expression
of different genes when expressed in NIH3T3
cells (5). The 18 kDa rat sequence has 98% amino acid (aa) identity with mouse, and 96 97%
aa identity with human,
bovine and sheep FGF basic (6, 7). Autocrine, intracrine and paracrine actions of FGF basic have been identified. Binding of FGF to heparin or cell surface HSPG is
necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysaccharides and lipids with lower affinity (3).
Expression of FGF basic is nearly ubiquitous but disruption of the mouse FGF basic gene gives a relatively mild phenotype, suggesting compensation by other FGF
family members. FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal
function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis reminiscent of a variety of pathological
conditions (1 3).
References:
1. Coulier, F. et al. (1997) J. Mol. Evol. 44:43.
2. Fernig, D. et al. (1994) Prog. Growth Factor Res. 5:353.
3. Presta, M. et al. (2005) Cytokine Growth Factor Rev. 16:159.
4. Claus, P. et al. (2003) J. Biol. Chem. 278:479.
5. Quarto, N. et al. (2005) Gene 356:49.
6. Tsuneto, M. et al. (2005) Biochem. Biophys. Res. Commun. 335:1239.
7. Shimasaki, S. et al. (1988) Biochem. Biophys. Res. Commun. 157:256.
Recombinant Rat FGF basic
Catalog Number: 3339-FB
 

 

上海力敏實業(yè)有限公司代理R&D產(chǎn)品,咨詢 
上海力敏實業(yè)有限公司代理R&D產(chǎn)品,咨詢 


留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算結(jié)果(填寫阿拉伯數(shù)字),如:三加四=7
性工具酷刑虐女惨叫小说| 国产亚洲精品资源在线26U| 亚洲日韩欧美一区二区三区| av网站在线观看| 色AV综合AV综合无码网站| 无码人妻丰满熟妇区96| 中文字幕人妻色偷偷久久| 在线毛片片免费观看| 日本熟妇乱人伦XXXX| 成人小说亚洲一区二区三区| 嬌小bbw搡bbbb搡bbbb| 图片 小说 校园 激情 都市| 欧美亚洲色综久久精品国产| 西瓜视频高清在线观看免费| 国产成人午夜精品久久久久久 | 少妇连续高潮抽搐| 亚洲国产另类久久久精品黑人| 中国人体棚拍室内摄影| 门卫老头吮她的花蒂| 无码人妻精品一区二区三区在线| 一夜未拔h-山里猎户| 久久精品丝袜高跟鞋| 把她日出水来好爽太紧了| 亚洲AV影院一区二区三区| 成人午夜又粗又硬又长| 欧美极度残忍变态另类| 国产FREEXXXX性播放麻豆| 被强迫各种姿势侵犯N| 亚洲精品乱码久久久久久按摩 | 野外真人实战cs| 无码人妻AV一二区二区三区| 毛片在线播放a| 免费a级毛片无码无遮挡| 地铁跑酷国际服下载| 中文字幕无码无码专区| yin荡娇妻乱部分阅读| 欧美性性性性性色大片免费的 | 亚洲精品动漫免费二区| 丰满少妇被猛烈进入高清播放| 国产精品女a片爽爽波多洁衣| 色噜噜综合亚洲AV中文无码|