国产综合一区二区三区,99香蕉国产精品偷在线观看,性色少妇AV蜜臀人妻无码,成版人app网站

您好,歡迎進(jìn)入上海力敏實(shí)業(yè)有限公司網(wǎng)站!
一鍵分享網(wǎng)站到:
您現(xiàn)在的位置:首頁(yè) >> 產(chǎn)品中心 >> 生化試劑、抗體、血清 >> 細(xì)胞因子 >> R&D 416-mlRecombinant Mouse M-CSF巨噬細(xì)胞集落刺激因子

Recombinant Mouse M-CSF巨噬細(xì)胞集落刺激因子

  • 更新時(shí)間:  2023-07-24
  • 產(chǎn)品型號(hào):  R&D 416-ml
  • 簡(jiǎn)單描述
  • Recombinant Mouse M-CSF巨噬細(xì)胞集落刺激因子
    上海力敏代理R&D產(chǎn)品,美國(guó)*Recombinant Mouse M-CSF,Recombinant human M-CSF,規(guī)格分別是10ug和50ug 咨詢
    還有人的Human M-CSF
詳細(xì)介紹

Recombinant Mouse M-CSF巨噬細(xì)胞集落刺激因子

MCSF,
also known as CSF1,
is a fourαhelicalbundle
cytokine that is the primary regulator of macrophage survival, proliferation and differentiation (1 3).
MCSF
is also essential for the survival and proliferation of osteoclast progenitors (1, 4). MCSF
also primes and enhances macrophage killing of tumor cells and
microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis (2, 3). MCSF
increases during
pregnancy to support implantation and growth of the decidua and placenta (5). Sources of MCSF
include fibroblasts, activated macrophages, endometrial secretory
epithelium, bone marrow stromal cells and activated endothelial cells (1 5).
The MCSF
receptor (cfms)
transduces its pleotropic effects and mediates its
endocytosis. MCSF
mRNAs of various sizes occur (3 9).
Full length mouse MCSF
transcripts encode a 520 amino acid (aa) type I transmembrane (TM) protein with
a 462 aa extracellular region, a 21 aa TM domain, and a 37 aa cytoplasmic tail that forms a 140 kDa covalent dimer. Differential processing produces two
proteolytically cleaved, secreted dimers. One is an Nand
Oglycosylated
86 kDa dimer, while the other is modified by both glycosylation and chondroitinsulfate
proteoglycan (PG) to generate a 200 kDa subunit. Although PGmodified
MCSF
can circulate, it may be immobilized by attachment to type V collagen (8). Shorter
transcripts encode M CSF
that lacks cleavage and PG sites and produces an Nglycosylated
68 kDa TM dimer and a slowly produced 44 kDa secreted dimer (7).
Although forms may vary in activity and halflife,
all contain the Nterminal
150 aa portion that is necessary and sufficient for interaction with the M CSF
receptor
(10, 11). The first 229 aa of mature mouse MCSF
shares 87%, 83%, 82% and 81% aa identity with corresponding regions of rat, dog, cow and human MCSF,
respectively (12, 13). Human MCSF
is active in the mouse, but mouse MCSF
is reported to be speciesspecific

Recombinant Mouse M-CSF巨噬細(xì)胞集落刺激因子

 

上海力敏R&D一級(jí)代理咨詢 


留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
无码精品av久久久奶水| 综合自拍亚洲综合图区av| YSL千人千色短视频专区| 插插网| 天天爽夜夜爽人人爽一区二区| 国产成人精品一区二区三区无码| 野花免费视频完整版在线播放 | 99久久久无码国产精品不卡| 精品久久亚洲中文无码色欲av | 无码精品一区二区三区在线| 意大利电影奸情| 公翁的粗大放进我的秘密电影| 不许穿内裤随时挨C| 初小videos第一次摘花| 中文字幕精品无码亚洲字幕蜜芽| 男人桶女人30分钟| 久久婷婷激情综合色综合俺也去| gogo人体大胆瓣开下部l| 香港三级台湾三级在线播放| 色欧美片视频在线观看| 弥留之国的爱丽丝第一季| 精品国产一区二区三区无码| 免费看一区二区三区四区| 日本巜侵犯人妻人伦| 最近2019中文字幕MV免费看| 亚洲色久国产精品久久久久影院| 哦┅┅快┅┅用力啊┅┅动态图 | 国产人妻无码一区二区三区不卡 | 无码欧美人XXXXXBBBBB| 风油精的作用和功效| 少妇挑战三个黑人惨叫4p国语| 永久免费无码网站在线观看个| 中国极品艳妇av少妇hd| 久热这里只有精品视频6 | 成人av在线观看| 中文字幕在线无码一区二区三区| 久久天天躁狠狠躁夜夜躁2014 | 苍井そら无码av| 熟妇人妻AV无码一区二区三区 | 99精品无码一区二区毛片免费| 欧美极度残忍变态另类电影|